Category Archives: molecular biology

SSRIs – A landmark in neuro-pharmacology - adidarwinian

Selective Serotonin Reuptake Inhibitors (SSRIs) – A Landmark

Updated on June 08, 2015

Selective Serotonin Reuptake Inhibitors (SSRIs) – A Landmark in Neuro-pharmacology!!

SSRIs - A Landmark in Neuro-pharmacology - adidarwinian

SSRIs – A Landmark in Neuro-pharmacology – adidarwinian

If a pharmacologist (a person who specializes in the study of the medicines, that is, Pharmacology) has to name one of the finest medical marvels in the history of Neuro-pharmacology (Neuro-pharmacology is the study of the medicines that affect the nervous system), then the development of the class of medicines known as the Selective Serotonin Reuptake Inhibitors (SSRIs) is certainly the correct and the most rational answer. These medicines have rejuvenated the whole realm of therapeutic intervention for the Psychiatric disorders or Psychiatric Diseases (Psychiatric diseases or disorders are the diseases causing some sort of disturbances in the brain of a person, and thus, resulting in changes in behavior, emotions, thought process, comprehension, and other mental faculties of the affected person).

It is now very clearly acknowledged by the psychiatric community that serotonin (a neurotransmitter) really exerts a major influence in maintaining the Homeostasis (equilibrium or stability) in the Neural Circuitry (the inter-network of the brain cells or neurons) of our brains. The Mechanism of Action (MOA) of SSRIsSelective Serotonin Reuptake Inhibitors (SSRIs) rectify the disordered neuronal biochemistry by blocking the serotonin reuptake pump or serotonin transporter protein (SERT). This results in the selective inhibition of the reuptake of serotonin in the brain neurons, and hence, increases the amount of serotonin in the space (synaptic cleft) between the brain’s neurons.

Fluoxetine, Fluvoxamine, Citalopram, Escitalopram, Paroxetine, and Sertraline are the medicines that belong to the Selective Serotonin Reuptake Inhibitors (SSRIs) class.

Selective Serotonin Reuptake Inhibitors or SSRIs class of medicines has become the mainstay therapy for treating Depression, Anxiety Disorders such as the Obsessive Compulsive Disorder or OCD. Their potential in treating Psychoses has also been implicated. (Psychoses is plural of Psychosis, which is defined as a mental disorder characterized by the symptoms, such as, delusions (false beliefs) or hallucinations (hearing or seeing things which are not actually there), that indicate loss of contact or impaired contact with the reality.)

Books To Read–

Traumatic Relationships and Serious Mental Disorders at Amazon.com

Coping With Depression: From Catch-22 to Hope at Amazon.com

Mindfulness for Beginners: Reclaiming the Present Moment–and Your Life at Amazon.com

The Mindful Way through Depression: Freeing Yourself from Chronic Unhappiness at Amazon.com

Adidarwinian - Motive Behind The Creation

Adidarwinian – The Motive Behind The Creation

Updated – October, 2013

THE MOTIVE BEHIND THE CREATION OF ADIDARWINIAN.COM (Adidarwinian – Health, Biology, Science)

THIS BLOG / WEBSITE HAS BEEN CREATED IN THE HONOR OF THE GREATEST BIOLOGIST EVER BORN IN ENTIRE THE HISTORY OF MANKIND – Sir CHARLES DARWIN

Adidarwinian – Health, Biology, Science is a scientific platform which provides original scientific information, in a lucid way, about Health, Wellness, Fitness, Medicine, Pharmacology, Homeopathy, Herbal Medicine or Herbs, Natural Medicine, Alternative medicine, Biology, Charles Darwin, Bioinformatics, Computational Biology, Biotechnology, Molecular Biology,and allied sciences. As the content is comprehensive, at times, yet always lucid, this helps laymen in understanding the most complex topics easily. The website – Adidarwinian – facilitates understanding of Medical and Biological sciences at all levels.