Give Mechanism of Action of Venlafaxine

Tagged: 5HT, first SNRI, inhibition of 5HT reuptake, inhibition of NE reuptake, Mechanism of Action of Venlafaxine, MOA of Venlafaxine, NE, norepinephrine, norepinephrine reuptake, serotonin, Serotonin Norepinephrine Reuptake Inhibitor, serotonin reuptake, SNRI, venlafaxine

This topic has 1 reply, 2 voices, and was last updated 8 years, 11 months ago by Dr. Aditya Sardana.

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- 22/05/2015 at 7:24 pm #3936
  tony
  Participant
  Give Mechanism of Action of Venlafaxine. What is the mechanism of action – MOA of Venlafaxine?
- 22/05/2015 at 7:35 pm #3937
  Dr. Aditya Sardana
  Keymaster
  Reply To Give Mechanism of Action of Venlafaxine – MOA of Venlafaxine
  Venlafaxine is the first SNRI (Serotonin Norepinephrine Reuptake Inhibitor) marketed in the United States of America. Venlafaxine acts by inhibition of 5HT reuptake (serotonin reuptake) and inhibition of NE reuptake (norepinephrine reuptake).
  
  Depending on the dose of venlafaxine, it exhibits different degrees of inhibition of serotonin reuptake versus inhibition of norepinephrine reuptake. Inhibition of 5HT reuptake is present even at low doses whereas NE reuptake is seen at higher doses.
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